Peter Reddien
نویسنده
چکیده
Peter Reddien attended graduate school at MIT in the lab of Bob Horvitz, studying programmed cell death in Caenorhabditis elegans. He carried out postdoctoral work with Alejandro Sánchez Alvarado at the University of Utah, where he performed the fi rst planarian RNA interference screen. He started his lab at the Whitehead Institute and the Department of Biology at MIT in 2005 and is an HHMI Investigator. His major area of research interest is studying the molecular and cellular mechanisms that control regeneration.
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متن کاملDeveloment and Stem Cells
INTRODUCTION Planarians are capable of regenerating any missing body part and are an emerging system for investigation of cellular and molecular mechanisms underlying regeneration. Regeneration requires production of new cells and instructions that specify the identity of cell types to be regenerated. The planarian Schmidtea mediterranea utilizes a population of dividing regenerative cells call...
متن کاملSMEDWI-2 is a PIWI-like protein that regulates planarian stem cells.
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متن کاملWnt Signaling and the Polarity of the Primary Body Axis
How animals establish and pattern the primary body axis is one of the most fundamental problems in biology. Data from diverse deuterostomes (frog, fish, mouse, and amphioxus) and from planarians (protostomes) suggest that Wnt signaling through beta-catenin controls posterior identity during body plan formation in most bilaterally symmetric animals. Wnt signaling also influences primary axis pol...
متن کاملSpecialized progenitors and regeneration.
Planarians are flatworms capable of regenerating all body parts. Planarian regeneration requires neoblasts, a population of dividing cells that has been studied for over a century. Neoblast progeny generate new cells of blastemas, which are the regenerative outgrowths at wounds. If the neoblasts comprise a uniform population of cells during regeneration (e.g. they are all uncommitted and plurip...
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ورودعنوان ژورنال:
- Current Biology
دوره 25 شماره
صفحات -
تاریخ انتشار 2015